Cryotherapy and immune checkpoint inhibitor therapy for the treatment of metastatic non-small cell lung cancer

  • Gediminas Vasiliauskas Department of Pulmonology, Lithuanian University of Health Sciences
  • Evelina Sabeckytė Department of Laboratory Medicine, Lithuanian University of Health Sciences
  • Erika Skrodenienė Department of Laboratory Medicine, Lithuanian University of Health Sciences
  • Lina Poškienė Department of Pathology, Lithuanian University of Health Sciences
  • Skaidrius Miliauskas Department of Pulmonology, Lithuanian University of Health Sciences
  • Marius Žemaitis Department of Pulmonology, Lithuanian University of Health Sciences
Reikšminiai žodžiai: lung cancer, cryotherapy, immunotherapy

Santrauka

Lung cancer remains among the most frequently diagnosed and deadliest diseases in the world. While immune checkpoint inhibitors revolutionized the cancer treatment landscape, only a relatively small proportion of patients benefit from this treatment, likely due to the ability of cancer cells to evade or even exclude the immune system from tumors. Cryotherapy offers a possible way to counteract this process by inducing an inflammatory response and helping in cancer neoantigen presentation, increasing the effectiveness of immunotherapy. While preclinical studies seem to support this claim, further investigation is needed to conclude the benefits and risks of cryotherapy in combination with immune checkpoint inhibitors.

Kaip cituoti
1.
Vasiliauskas G, Sabeckytė E, Skrodenienė E, Poškienė L, Miliauskas S, Žemaitis M. Cryotherapy and immune checkpoint inhibitor therapy for the treatment of metastatic non-small cell lung cancer [Prieiga per internetą]. PIA 2023 rugs.;7(2):157-163.[žiūrėta 2024 birž. 18 ] Available from: http://pia.pulmoalerg.lt/index.php/PIA/article/view/1262
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