LATEX ALLERGY

Abstract

The widespread use of latex products in the last 25 years increases IgE mediated sensitization. The incidence of latex allergy in the general population is 1-2 proc., but latex allergy is often diagnosed for certain profession people (health care workers, people working in rubber industry). Particularly high risk to develop latex allergy is for those who work in operating rooms, laboratories and haemodialysis centres. Risk factors for latex allergy include patients with spina bifida, those who have multiple surgeries, atopy, previous hand dermatitis or eczema and patients who have allergy to vegetables and fruits. Pathogenesis of latex allergy can be I type immediate reaction, IV type delayed reaction and non-immune response. This determines what kind of symptoms appear. Clinical manifestation differs from skin reactions to anaphylactic shock. The aim of this article is to review mechanisms of development of latex allergy, its clinical manifestation and risk factors, methods of diagnostics and treatment and epidemiological data.