CARBOPLATIN HYPERSENSITIVITY: SUCCESSFUL PERSONALIZED SCHEME OF DESENSITIZATION. CLINICAL CASE.

  • Justina Šematonytė LSMU MA Imunologijos ir alergologijos klinika
  • Ieva Bajoriūnienė LSMU MA Imunologijos ir alergologijos klinika
  • Simona Kašinskaitė LSMU MA Imunologijos ir alergologijos klinika
Keywords: carboplatin hypersensitivity, desensitization, ovarian carcinoma

Abstract

Hypersensitivity reactions to carboplatin occur in up to 44% of patients during the third-line chemotherapy treatment. The most common hypersensitivity reactions are IgE-mediated (type I). Desensitization allows patients with drug allergies to receive the sensitizing drug. The article presents the clinical case of a 38-year-old female with stage IV ovarian cancer. Hypersensitivity reactions to carboplatin developed during the treatment. The patient was consulted by an allergist and clinical immunologist. The desensitization of carboplatin was prescribed. However, the allergist and clinical immunologist achieved the challenge to find a successful personalized scheme. Prolonged desensitization provided an opportunity to complete the planned chemotherapy and improve the patient’s quality of life.

How to Cite
1.
Šematonytė J, Bajoriūnienė I, Kašinskaitė S. CARBOPLATIN HYPERSENSITIVITY: SUCCESSFUL PERSONALIZED SCHEME OF DESENSITIZATION. CLINICAL CASE. [Internet]. PIA 2021 Sep.;5(2):131–137.[cited 2024 Nov. 22 ] Available from: http://pia.pulmoalerg.lt/index.php/PIA/article/view/760
Issue
Vol 5 No 2 (2021): Pulmonology and Allergology
Section
Pulmonology and allergology